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          • Primary Antibodies ›
          • H3K36me2/3 Antibodies

          Proteintech

          H3K36me2/3 Recombinant Rabbit Monoclonal Antibody (241139G6), CoraLite® Plus 488

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          Cite H3K36me2/3 Recombinant Rabbit Monoclonal Antibody (241139G6), CoraLite® Plus 488

          Additional Information:
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          • Antibody Testing Data (1)
          H3K36me2/3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          H3K36me2/3 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          H3K36me2/3 Antibody (CL488-84329) in ICC/IF

          Immunofluorescent analysis of (4% PFA) fixed HeLa cells using CoraLite Plus 488 Di/Tri-Methyl-Histone H3 (Lys36) antibody (CL488-84329, Clone: 241139G6 ) at dilution of 1:200, CL594-Phalloidin (red). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          H3K36me2/3 Antibody in Immunocytochemistry (ICC/IF)

          Product Details

          CL488-84329

          Applications
          Tested Dilution
          Publications

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Expression System

          CHO cells

          Class

          Recombinant Monoclonal

          Type

          Antibody

          Clone

          241139G6

          Immunogen

          Peptide

          Conjugate

          CoraLite® Plus 488 CoraLite® Plus 488 CoraLite® Plus 488
          • Unconjugated
          • Request custom conjugation

          Excitation/Emission Max

          493/522 nm

          Form

          Liquid

          Concentration

          1000 µg/mL

          Amount

          100 µg

          Purification

          Affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol, 0.5% BSA

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, store in dark

          Shipping conditions

          Wet ice

          Target Information

          Histones are small, highly basic proteins that consist of a globular domain with unstructured N- and C-terminal tails protruding from the main structure. Histone H3 is one of the five main histones that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. In addition to their role in DNA compartmentalization, histones also play crucial roles in various biologic processes, including gene expression and regulation, DNA repair, chromatin condensation, cell cycle progression, chromosome segregation, and apoptosis. The ability of histones to regulate chromatin dynamics primarily originates from various posttranslational modifications carried out by histone-modifying enzymes.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: H3 histone family, member A; H3 histone family, member B; H3 histone family, member C; H3 histone family, member D; H3 histone family, member F; H3 histone family, member H; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; HIST1H3A; HIST1H3E; HIST1H3F; histone 1, H3a; histone 1, H3b; histone 1, H3c; histone 1, H3d; histone 1, H3e; histone 1, H3f; histone 1, H3g; histone 1, H3h; histone 1, H3i; histone cluster 1 H3 family member a; histone cluster 1 H3 family member b; histone cluster 1 H3 family member c; histone cluster 1 H3 family member d; histone cluster 1 H3 family member e; histone cluster 1 H3 family member f; histone cluster 1 H3 family member g; histone cluster 1 H3 family member h; histone cluster 1 H3 family member i; histone cluster 1, H3a; histone cluster 1, H3b; histone cluster 1, H3c; histone cluster 1, H3d; histone cluster 1, H3e; histone cluster 1, H3f; histone cluster 1, H3g; histone cluster 1, H3h; histone cluster 1, H3i; Histone H3.1; Histone H3/a; Histone H3/b; Histone H3/c; Histone H3/d; Histone H3/f; Histone H3/h; Histone H3/i; Histone H3/j; Histone H3/k; Histone H3/l; unnamed protein product

          View more View less

          Gene Aliases: H3.1; H3.f; H3/A; H3/b; H3/c; H3/d; H3/f; H3/h; H3/i; H3/k; H3/l; H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3F1K; H3FA; H3FB; H3FC; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J

          View more View less

          UniProt ID: (Human) P68431

          View more View less

          Entrez Gene ID: (Human) 8350, (Human) 8357, (Human) 8354, (Human) 8358, (Human) 8352, (Human) 8351, (Human) 8353, (Human) 8968, (Human) 8355

          View more View less

          Function(s)
          DNA binding protein binding structural constituent of chromatin cadherin binding protein heterodimerization activity
          Process(es)
          chromatin organization nucleosome assembly gene expression telomere organization regulation of gene expression, epigenetic
          It has to be done as per old AB suggested Products section.

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