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          • Primary Antibodies ›
          • Thyroglobulin Antibodies

          Proteintech

          Thyroglobulin Monoclonal Antibody (4D3C5), CoraLite® 594

          View all (40) Thyroglobulin antibodies

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          Cite Thyroglobulin Monoclonal Antibody (4D3C5), CoraLite® 594

          Additional Information:
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          • Antibody Testing Data (2)
          Thyroglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Thyroglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          Thyroglobulin Antibody (CL59460272100UL) in IHC (P)

          Immunofluorescent analysis of (4% PFA) fixed human thyroid cancer tissue using CoraLite 594 Thyroglobulin antibody (Product # CL59460272100UL), Clone: 4D3C5 ) at dilution of 1:200. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Thyroglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Thyroglobulin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

          Product Details

          CL59460272100UL

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Mouse / IgG2a

          Class

          Monoclonal

          Type

          Antibody

          Clone

          4D3C5

          Conjugate

          CoraLite® 594 CoraLite® 594 CoraLite® 594
          • Unconjugated
          • CoraLite Plus 488
          • Request custom conjugation

          Excitation/Emission Max

          593/614 nm

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Protein A

          Storage buffer

          PBS, pH 7.3, with 0.5% BSA, 50% glycerol

          Contains

          0.05% ProClin 300

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles, store in dark

          Shipping conditions

          Wet ice

          Target Information

          The human thyroglobulin (hTg) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones, T4 and T3. Thyroid disorders are, in large part, due to autoimmune origin, and anti-thyroglobulin autoantibodies were the first factor to be discovered. Anti-hTG is found in all thyroid autoimmune diseases (Hashimoto thyroiditis, Graves diseases), with the highest level observed in Hashimoto thyroiditis. Anti-hTG is also characteristic of thyroid cancer, and its determination can be used for the follow up of cancer patients.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Colloid; Tg; Thyroglobulin; unnamed protein product

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          Gene Aliases: AITD3; TG; TGN

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          UniProt ID: (Human) P01266

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          Entrez Gene ID: (Human) 7038

          View more View less

          Function(s)
          hormone activity protein binding identical protein binding
          Process(es)
          thyroid hormone generation signal transduction iodide transport thyroid gland development regulation of myelination thyroid hormone metabolic process hormone biosynthetic process
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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