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Rockland
CTRP3 Polyclonal Antibody
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FIGURE: 1 / 3
CTRP3 Antibody (600-401-AP9) in ICC/IF
Immunofluorescence Microscopy of CTRP3 antibody. Cell Type: mouse heart cells. Fixation: 0.5% PFA. Antigen retrieval: not required. Primary antibody: CTRP3 antibody at 10 µg/mL for 1 hr at RT. Secondary antibody: Fluorescein rabbit secondary antibody at 1:10,000 for 45 min at RT. Localization: CTRP3 is secreted. Staining: CTRP3 as red fluorescent signal.
Product Details
600-401-AP9
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-CTRP3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a 16 amino acid synthetic peptide from near the internal region of human CTRP3.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Multiple isoforms of human CTRP3 have been reported. It has been suggested that CTRP3 may play a role in skeletal development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: cartducin; cartonectin; Collagenous repeat-containing sequence 26 kDa protein; collagenous repeat-containing sequence of 26-kDa; Complement C1q tumor necrosis factor-related protein 3; CORS26; Secretory protein CORS26
Gene Aliases: 2310005P21Rik; C1ATNF3; C1QTNF3; CORCS; CORS; CORS-26; CORS26; CTRP3; UNQ753/PRO1484
UniProt ID: (Human) Q9BXJ4, (Mouse) Q9ES30
Entrez Gene ID: (Human) 114899, (Mouse) 81799
negative regulation of gene expression
cellular triglyceride homeostasis
negative regulation of NF-kappaB import into nucleus
glucose homeostasis
negative regulation of gluconeogenesis
positive regulation of cytokine secretion
negative regulation of inflammatory response
protein oligomerization
positive regulation of protein kinase B signaling
positive regulation of adiponectin secretion
protein trimerization
positive regulation of ERK1 and ERK2 cascade
negative regulation of monocyte chemotactic protein-1 production
negative regulation of interleukin-6 secretion
fat cell differentiation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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