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Invitrogen
Calcyclin Polyclonal Antibody
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FIGURE: 1 / 10
Calcyclin Antibody (PA5-117823) in ICC/IF
Immunofluorescence staining of Calcyclin in A431 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with Calcyclin Polyclonal Antibody (Product # PA5-117823, 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive stain... View More
Product Details
PA5-117823
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
E. coli-derived Human Siah-interacting protein/CacyBP fragment
Conjugate
Form
Liquid
Purification
Antigen affinity chromatography, Protein A
Storage buffer
PBS, pH 7
Contains
0.03% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Calcyclin is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-dependent insulin release, stimulation of prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of this gene have been implicated in melanoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2A9; 5B10; CABP; CACY; CacyBP; Calcyclin; Calcyclin-binding protein; GIG5; growth-inhibiting gene 5 protein; hCacyBP; PRA; putative differentiation related protein in glioma cell line BT-325; RP1-102G20.6; S100A6; S100A6-binding protein; Siah-interacting protein; Siah-interacting protein (SIP); unnamed protein product
Gene Aliases: CACYBP; GIG5; PNAS-107; S100A6BP; SIP
UniProt ID: (Human) Q9HB71
Entrez Gene ID: (Human) 27101
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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