Search
Proteintech
DNA2 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
Product Details
21599-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DNA2 Fusion Protein Ag16206 (1-350 aa encoded by BC111740)
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
37.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to DNA2.
Immunogen sequence: MEQLNELEL LMEKSFWEEA ELPAELFQKK VVASFPRTVL STGMDNRYLV LAVNTVQNKE GNCEKRLVIT ASQSLENKEL CILRNDWCSV PVEPGDIIHL EGDCTSDTWI IDKDFGYLIL YPDMLISGTS IASSIRCMRR AVLSETFRSS DPATRQMLIG TVLHEVFQKA INNSFAPEKL QELAFQTIQE IRHLKEMYRL NLSQDEIKQE VEDYLPSFCK WAGDFMHKNT STDFPQMQLS LPSDNSKDNS TCNIEVVKPM DIEESIWSPR FGLKGKIDVT VGVKIHRGYK TKYKIMPLEL KTGKESNSIE HRSQVVLYTL LSQERRADPE AGLLLYLKTG QMYPVPANHL D (1-350 aa encoded by BC111740)
Target Information
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA2 DNA replication helicase 2-like; DNA2-like helicase; hDNA2; KIAA0083
Gene Aliases: DNA2; DNA2L; E130315B21Rik; hDNA2; KIAA0083; RTS4
UniProt ID: (Human) P51530, (Mouse) Q6ZQJ5
Entrez Gene ID: (Human) 1763, (Mouse) 327762
nucleotide binding
DNA binding
DNA helicase activity
RNA binding
catalytic activity
helicase activity
nuclease activity
endonuclease activity
protein binding
ATP binding
hydrolase activity
ATPase activity
5'-flap endonuclease activity
single-stranded DNA-dependent ATP-dependent DNA helicase activity
deoxyribonuclease (pyrimidine dimer) activity
5'-3' DNA helicase activity
metal ion binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
site-specific endodeoxyribonuclease activity, specific for altered base
phosphoric ester hydrolase activity
single-stranded DNA-dependent ATPase activity
T/G mismatch-specific endonuclease activity
retroviral 3' processing activity
DNA replication checkpoint
telomere maintenance
DNA double-strand break processing
DNA replication
mitochondrial DNA replication
DNA repair
base-excision repair
cellular response to DNA damage stimulus
telomere maintenance via semi-conservative replication
DNA geometric change
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
replication fork reversal
t-circle formation
mitotic telomere maintenance via semi-conservative replication
metabolic process
DNA duplex unwinding
nucleic acid phosphodiester bond hydrolysis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support