Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Immunogen sequence: RIVKVMDDYQ VMDEFLYNLS SDDFNDKWIA SNWPSKILGQ IELVQQQHVE DEEKFRKIQI MDQNNFQEKL EGLQLVVAGF S
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 85%.
This gene encodes an inner dynein arm heavy chain that provides structural support between the radial spokes and the outer doublet of the sperm tail. Naturally occurring mutations in this gene are associated with primary ciliary dyskinesia and multiple morphological anomalies of the flagella that result in asthenozoospermia and male infertility. Mice with a homozygous knockout of the orthologous gene are viable but have reduced sperm motility and are infertile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; DNAH1 variant protein; Dynein axonemal heavy chain 1; dynein, axonemal, heavy chain 1; dynein, axonemal, heavy polypeptide 1; hDHC7; Heat shock regulated protein 1; HSRF-1; testicular tissue protein Li 60
Gene Aliases: DHC7; DNAH1; DNAHC1; HDHC7; HL-11; HL11; HSRF-1; KIAA1410; XLHSRF-1
UniProt ID: (Human) Q9P2D7
Entrez Gene ID: (Human) 25981
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