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Proteintech
DPF2 Polyclonal Antibody
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Product Details
12111-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DPF2 Fusion Protein Ag2756 (1-391 aa encoded by BC014889)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAAVVENVV KLLGEQYYKD AMEQCHNYNA RLCAERSVRL PFLDSQTGVA QSNCYIWMEK RHRGPGLASG QLYSYPARRW RKKRRAHPPE DPRLSFPSIK PDTDQTLKKE GLISQDGSSL EALLRTDPLE KRGAPDPRVD DDSLGEFPVT NSRARKRILE PDDFLDDLDD EDYEEDTPKR RGKGKSKGKG VGSARKKLDA SILEDRDKPY ACDICGKRYK NRPGLSYHYA HSHLAEEEGE DKEDSQPPTP VSQRSEEQKS KKGPDGLALP NNYCDFCLGD SKINKKTGQP EELVSCSDCG RSGHPSCLQF TPVMMAAVKT YRWQCIECKC CNICGTSEND DQLLFCDDCD RGYHMYCLTP SMSEPPEGSW SCHLCLDLLK EKASIYQNQN SS (1-391 aa encoded by BC014889)
Target Information
The protein encoded by this gene is a member of the d4 domain family, characterized by a zinc finger-like structural motif. This protein functions as a transcription factor which is necessary for the apoptotic response following deprivation of survival factors. It likely serves a regulatory role in rapid hematopoietic cell growth and turnover. This gene is considered a candidate gene for multiple endocrine neoplasia type I, an inherited cancer syndrome involving multiple parathyroid, enteropancreatic, and pituitary tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Apoptosis response zinc finger protein; BAF45D; BRG1-associated factor 45D; D4, zinc and double PHD fingers family 2; neuro-d4/requiem; Protein requiem; requiem; requiem, apoptosis response zinc finger; unnamed protein product; Zinc finger protein ubi-d4; zinc finger; contains one C2H2 and two C4HC3
Gene Aliases: 2210010M07Rik; BAF45D; CSS7; DPF2; REQ; SMARCG2; ubi-d4; UBID4
UniProt ID: (Human) Q92785, (Mouse) Q61103
Entrez Gene ID: (Human) 5977, (Rat) 361711, (Mouse) 19708
transcription corepressor activity
protein binding
zinc ion binding
metal ion binding
histone H3K9me2/3 reader activity
histone H3K14ac reader activity
histone H4K16ac reader activity
RNA polymerase II core promoter proximal region sequence-specific DNA binding
molecular_function
histone modifying enzyme
negative regulation of transcription from RNA polymerase II promoter
chromatin organization
chromatin remodeling
regulation of transcription from RNA polymerase II promoter
apoptotic process
nervous system development
regulation of mitotic metaphase/anaphase transition
regulation of G0 to G1 transition
apoptotic signaling pathway
positive regulation of stem cell population maintenance
negative regulation of myeloid progenitor cell differentiation
regulation of G1/S transition of mitotic cell cycle
positive regulation of double-strand break repair
regulation of nucleotide-excision repair
biological_process
transcription, DNA-templated
regulation of transcription, DNA-templated
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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