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Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:400 | - |
Immunohistochemistry (Frozen) (IHC (F)) |
1:300 | - |
Immunocytochemistry (ICC/IF) |
Assay-dependent | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Guinea pig / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Peptide corresponding to amino acid residues 372-385 of rat DRD1 (Intracellular, C-terminus) |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.8 mg/mL |
Storage conditions |
-20°C |
RRID |
AB_2857238 |
Reconstitute antibody with 50 µL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Peptide sequence is: SSHHEPRGSI SKDC
Homology: Mouse, dog, pig amino acid residues identical; human - 13/14 amino acid residues identical.
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D(1A) dopamine receptor; D1 receptor; D1A dopamine receptor; D1a receptor; Dopamine 1 receptor; Dopamine D1 receptor; dopamine receptor D1A; Dopamine-1A receptor; G protein-coupled receptor DRD1
Gene Aliases: DRD1; Drd1a; Gpcr15
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