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Product Details
PA5-47201
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Goat / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Mouse myeloma cell line NS0-derived recombinant human ECE-1 Gln90-Trp770 |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
0.2 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 5% trehalose |
Contains |
No Preservative |
Storage conditions |
-20° C, Avoid Freeze/Thaw Cycles |
RRID |
AB_2608782 |
Product Specific Information
In direct ELISAs and Western blots, approximately 5% cross-reactivity with recombinant human ECE-2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
ECE-1 is involved in proteolytic processing of endothelin precursors to biologically active peptides.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ECE 1; ECE-1; Endothelin-converting enzyme 1
Gene Aliases: ECE; ECE1
UniProt ID: (Human) P42892
Entrez Gene ID: (Human) 1889
Molecular Function:
metalloprotease
response to hypoxia
positive regulation of receptor recycling
regulation of systemic arterial blood pressure by endothelin
apoptotic process
heart development
positive regulation of cardiac muscle hypertrophy
substance P catabolic process
bradykinin catabolic process
calcitonin catabolic process
protein processing
peptide hormone processing
regulation of vasoconstriction
positive regulation of cAMP biosynthetic process
endothelin maturation
response to muscle stretch
regulation of vasodilation
hormone catabolic process
response to drug
embryonic digit morphogenesis
ear development
positive regulation of G-protein coupled receptor protein signaling pathway
response to cadmium ion
pharyngeal system development
regulation of ERK1 and ERK2 cascade
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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