PA5-30013 targets ECHS1 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-30013 immunogen is recombinant fragment corresponding to a region within amino acids 55 and 290 of Human ECHS1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The protein encoded by this gene functions in the second step of the mitochondrial fatty acid beta-oxidation pathway. It catalyzes the hydration of 2-trans-enoyl-coenzyme A (CoA) intermediates to L-3-hydroxyacyl-CoAs. The gene product is a member of the hydratase/isomerase superfamily. It localizes to the mitochondrial matrix. Transcript variants utilizing alternative transcription initiation sites have been described in the literature.
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Protein Aliases: 1; enoyl CoA hydratase, short chain, 1, mitochondrial; enoyl Coenzyme A hydratase; enoyl Coenzyme A hydratase, short chain, 1, mitochondrial; enoyl-CoA hydratase; Enoyl-CoA hydratase 1; Enoyl-CoA hydratase, mitochondrial; enoyl-CoA hydratase, short chain, 1, mitochondrial; mitochondrial; SCEH; short chain; short chain enoyl-CoA hydratase; Short-chain enoyl-CoA hydratase
Gene Aliases: C80529; ECHS1; ECHS1D; SCEH