Immunogen sequence: QDCHSHSRTSL QSSHLWEFVR DLLLSPEENC GILEWEDREQ GIFRVVKSEA LAKMW
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 100%.
ELF5 is a member of an epithelium-specific subclass of the Ets transcritpion factor family. In addition to its role in regulating the later stages of terminal differentiation of keratinocytes, it appears to regulate a number of epithelium-specific genes found in tissues containing glandular epithelium such as salivary gland and prostate. It has very low affinity to DNA due to its negative regulatory domain at the amino terminus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: E74-like factor 5; E74-like factor 5 (ets domain transcription factor); ELF5; Epithelium-restricted ESE-1-related Ets factor; Epithelium-specific Ets transcription factor 2; ESE-2; ESE2; ETS-related transcription factor Elf-5
Gene Aliases: ELF5; ESE2
UniProt ID: (Human) Q9UKW6
Entrez Gene ID: (Human) 2001