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Invitrogen
EME1 Polyclonal Antibody
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Product Details
PA5-101988
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human EME1(Accession Q96AY2), corresponding to amino acid residues K108-N158.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total EME1.
Target Information
EME1 and MUS81 form an endonuclease complex that cleaves branched DNA structures, especially those arising during stalled DNA replication (Abraham et al., 2003).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Crossover junction endonuclease EME1; essential meiotic endonuclease 1 homolog 1; essential meiotic endonuclease 1 homolog 2; Essential meiotic structure-specific endonuclease 1; hMMS4; homolog of yeast EME1 endonuclease; MMS4 homolog; Msm4; SLX2 structure-specific endonuclease subunit homolog A; Structure-specific endonuclease subunit EME1; unnamed protein product
Gene Aliases: EME1; MMS4; MMS4L; SLX2A
UniProt ID: (Human) Q96AY2
Entrez Gene ID: (Human) 146956
resolution of meiotic recombination intermediates
telomere maintenance
DNA repair
double-strand break repair
DNA recombination
cellular response to DNA damage stimulus
replication fork processing
intra-S DNA damage checkpoint
resolution of mitotic recombination intermediates
response to intra-S DNA damage checkpoint signaling
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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