This antibody is specific to ENO3. It has no cross reaction to ENO1 and ENO2.
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme is found in skeletal muscle cells in the adult where it may play a role in muscle development and regeneration. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in this gene have be associated glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been described.
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Protein Aliases: 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolyase; Beta-enolase; enob; Enolase 3; enolase 3 (beta, muscle); MSE; muscle enriched enolase; Muscle specific enolase (beta beta enolose) (two splicing products); Muscle-specific enolase; Skeletal muscle enolase
Gene Aliases: BBE; Eno-3; ENO3; GSD13; MSE
Molecular Function: lyase