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Invitrogen
ETK Polyclonal Antibody
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Product Details
PA5-99532
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human BMX(Accession P51813), corresponding to amino acid residues C542-K592.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total BMX.
Target Information
Bone marrow tyrosine kinase (BMX) is a non-receptor tyrosine kinase that belongs to the SRC-related TEC subfamily of tyrosine kinases. It is an important regulator of various cellular processes including apoptosis, cell survival, cellular differentiation, cell migration, and transformation. One family of nonreceptor TKs includes the genes TEC (MIM 600583), TXK (MIM 600058), ITK (MIM 186973), and BTK (MIM 300300). All of these proteins are homologs of the Drosophila Src28 TK and contain an SH3 and SH2 domain upstream of the TK domain.[supplied by OMIM].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bmx; Bone marrow tyrosine kinase gene in chromosome X protein; Bone marrow tyrosine kinase gene in chromosome X protein homolog; BTK-like on X chromosome; Cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase; TYRO8 protein tyrosine kinase 8; unnamed protein product
Gene Aliases: BMX; ETK; Etk/Bmx; PSCTK2; PSCTK3; Tyro8
UniProt ID: (Human) P51813, (Mouse) P97504
Entrez Gene ID: (Human) 660, (Mouse) 12169
nucleotide binding
protein kinase activity
protein tyrosine kinase activity
non-membrane spanning protein tyrosine kinase activity
protein binding
ATP binding
zinc ion binding
kinase activity
transferase activity
metal ion binding
transferase activity, transferring phosphorus-containing groups
GTPase-activating protein
adaptive immune response
protein phosphorylation
phosphatidylinositol biosynthetic process
apoptotic process
cell adhesion
signal transduction
mesoderm development
intracellular signal transduction
protein autophosphorylation
B cell receptor signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
phosphorylation
peptidyl-tyrosine phosphorylation
cell differentiation
peptidyl-tyrosine autophosphorylation
regulation of cell proliferation
innate immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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