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Product Details
PA5-52943
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human FBP2
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2641523
Product Specific Information
Immunogen sequence: RKAGLAHLYG IAGSVNVTGD EVKKLDVLSN SLVINMVQSS YSTCVLVSEE NKDAIITAKE KRGKYVVCFD PLDG^M
^M
This product detects both FBP1 and FBP2, which are 80% homologous. The antigen sequence is a 100% match to FBP2 and the product has been validated against FBP1.^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 93%.
Target Information
FBP1 and FBP2 are gluconeogenesis regulatory enzymes which catalyze the hydrolosis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: D-fructose-1,6-bisphosphate 1-phosphohydrolase 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase 2; FBPase 1; FBPase 2; fructose-1; Fructose-1,6-bisphosphatase 1; fructose-1,6-bisphosphatase 2; Fructose-1,6-bisphosphatase isozyme 2; growth-inhibiting protein 17; hexosediphosphatase; Liver FBPase; Muscle FBPase; muscle fructose-bisphosphatase
Gene Aliases: FBP; FBP1; FBP2
UniProt ID: (Human) P09467, (Human) O00757
Entrez Gene ID: (Human) 2203, (Human) 8789
fructose metabolic process
fructose catabolic process
fructose 6-phosphate metabolic process
gluconeogenesis
regulation of gluconeogenesis
dephosphorylation
negative regulation of cell growth
cellular response to drug
negative regulation of glycolytic process
negative regulation of Ras protein signal transduction
protein homotetramerization
cellular response to magnesium ion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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