FGFBP3 is a heparin-binding protein which binds to FGF2, prevents binding of FGF2 to heparin and probably inhibits immobilization of FGF2 on extracellular matrix glycosaminoglycans, allowing its release and subsequent activation of FGFR signaling which leads to increased vascular permeability.
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Protein Aliases: FGF-binding protein 3; FGF-BP3; FGFBP-3; Fibroblast growth factor-binding protein 3
Gene Aliases: 2610306H15Rik; C10orf13; FGF-BP3; FGFBP3; PSEC0101