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Invitrogen
FUSIP1 Polyclonal Antibody
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Product Details
PA5-72926
Applications
Tested Dilution
Publications
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide made to an internal portion of human FUSIP1 (within residues 100-200). [Swiss-Prot# O75494]
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
SRSF10 (Serine and Arginine Rich Splicing Factor 10) is a member of the SR family of RNA-binding proteins that regulates alternative pre-mRNA splicing. It contains an RNA recognition motif (RRM) and a serine/arginine-rich (RS) domain that mediates RNA binding and protein-protein interactions within the spliceosome. SRSF10 functions as a context-dependent splicing regulator, capable of promoting or repressing exon inclusion depending on cellular conditions. Notably, it undergoes phosphorylation-dependent regulation, and during cellular stress or mitosis it can shift from an activator to a repressor of splicing. SRSF10 has been implicated in cell cycle control, apoptosis, metabolic regulation, and cancer-associated splicing alterations. Formerly known as FUSIP1 (FUS-interacting protein 1), SRSF10 is widely studied for its role in dynamic and stress-responsive RNA processing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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