Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:2,000 | View 4 publications 4 publications |
Immunoprecipitation (IP) |
0.5-4.0 µg | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Published species |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Frizzled 7 Fusion Protein Ag9446 (33-257 aa encoded by BC015915) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.33 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: QPYHGEKGI SVPDHGFCQP ISIPLCTDIA YNQTILPNLL GHTNQEDAGL EVHQFYPLVK VQCSPELRFF LCSMYAPVCT VLDQAIPPCR SLCERARQGC EALMNKFGFQ WPERLRCENF PVHGAGEICV GQNTSDGSGG PGGGPTAYPT APYLPDLPFT ALPPGASDGR GRPAFPFSCP RQLKVPPYLG YRFLGERDCG APCEPGRANG LMYFKEEERR FARLWV (33-257 aa encoded by BC015915)
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; Frizzled-7; Fz-7; FzE3; hFz7; mFz7; rizzled 7
Gene Aliases: Fz7; FZD7; FzE3
UniProt ID: (Human) O75084, (Mouse) Q61090
Entrez Gene ID: (Human) 8324, (Mouse) 14369, (Rat) 100360552
Molecular Function:
transmembrane signal receptor
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