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Product Details
PA5-75466
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 250-300 of Human GAS1.
Conjugate
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719194
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAS-1; growth arrest-specific 1; Growth arrest-specific gene-1; Growth arrest-specific protein 1
Gene Aliases: AW554192; Gas-1; GAS1
UniProt ID: (Human) P54826, (Mouse) Q01721
Entrez Gene ID: (Human) 2619, (Mouse) 14451, (Rat) 683470
cell cycle arrest
regulation of smoothened signaling pathway
negative regulation of protein processing
cellular response to vascular endothelial growth factor stimulus
regulation of apoptotic process
cell fate commitment
negative regulation of mitotic cell cycle
developmental growth
regulation of ER to Golgi vesicle-mediated transport
positive regulation of mesenchymal cell proliferation
cell cycle
axon guidance
positive regulation of cell proliferation
dorsal/ventral pattern formation
programmed cell death
cerebellum morphogenesis
dorsal/ventral neural tube patterning
negative regulation of cell growth
outer ear morphogenesis
middle ear morphogenesis
odontogenesis
embryonic digit morphogenesis
camera-type eye development
negative regulation of apoptotic process
negative regulation of smoothened signaling pathway
positive regulation of smoothened signaling pathway
eye morphogenesis
embryonic morphogenesis
embryonic cranial skeleton morphogenesis
embryonic skeletal system development
positive regulation of epithelial cell proliferation
negative regulation of epithelial cell proliferation
palate development
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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