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Invitrogen
GLUT2 Polyclonal Antibody
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FIGURE: 1 / 5
GLUT2 Antibody (PA5-97263) in WB
Western blot was performed using GLUT2 Polyclonal Antibody (Product # PA5-97263) and a 55 kDa, 60 kDa band corresponding to Slc2a2 was observed across cell lines tested. Membrane enriched extracts (30 µg lysate) of Hep G2 (Lane 1), Hep G2 treated with Insulin (5 µM for 4hrs) (Lane 2), Caco-2 (Lane 3), A-431 (Lane 4), A549 (Lane 5) and 769-P (Lane 6) as seen in (Fig. a) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX), 12 well. Resolved proteins were then transferred onto a nitrocellulose membrane (Product... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-97263
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: SW480, THP-1, Mouse liver, Mouse kidney, Rat liver; Cellular Location: Membrane, Multi-pass membrane protein
Target Information
Glucose transporter 2 isoform is an integral plasma membrane glycoprotein of the liver, islet beta cells, intestine, and kidney epithelium. It mediates facilitated bidirectional glucose transport. Because of its low affinity for glucose, it has been suggested as a glucose sensor. Mutations in the gene that encode this protein cause Fanconi-Bickel syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: glucose transporter; glucose transporter 2; glucose transporter type 2, liver; glucose transporter-like protein; GLUT-2; liver-type glucose transporter; solute carrier family 2 (facilitated glucose transporter), member 2; Solute carrier family 2 A2 (glucose transporter, type 2); unnamed protein product
Gene Aliases: Glut-2; GLUT2; GTT2
UniProt ID: (Human) P11168, (Mouse) P14246
Entrez Gene ID: (Human) 6514, (Mouse) 20526, (Rat) 25351
carbohydrate transport
carbohydrate utilization
fructose transport
galactose transport
positive regulation of insulin secretion involved in cellular response to glucose stimulus
transmembrane transport
dehydroascorbic acid transport
cellular response to fatty acid
glucose import across plasma membrane
glucose transmembrane transport
carbohydrate metabolic process
response to glucose
response to peptide hormone
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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