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Proteintech
GPD2 Polyclonal Antibody
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Product Details
17219-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
GPD2 Fusion Protein Ag11036 (5-378 aa encoded by BC019874)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: KAVKGTLVG GGALATVLGL SQFAHYRRKQ MNLAYVKAAD CISEPVNREP PSREAQLLTL QNTSEFDILV IGGGATGSGC ALDAVTRGLK TALVERDDFS SGTSSRSTKL IHGGVRYLQK AIMKLDIEQY RMVKEALHER ANLLEIAPHL SAPLPIMLPV YKWWQLPYYW VGIKLYDLVA GSNCLKSSYV LSKSRALEHF PMLQKDKLVG AIVYYDGQHN DARMNLAIAL TAARYGAATA NYMEVVSLLK KTDPQTGKVH VSGARCKDVL TGQEFDVRAK CVINATGPFT DSVRKMDDKD AAAICQPSAG VHIVMPGYYS PESMGLLDPA TSDGRVIFFL PWQKMTIAGT TDTPTDVTHH PIPSEEDINF ILNEV (5-378 aa encoded by BC019874)
Target Information
Mitochondrial glycerophosphate dehydrogenase (EC 1. 1. 99. 5), or GPD2, is located on the outer surface of the inner mitochondrial membrane and catalyzes the unidirectional conversion of glycerol-3-phosphate (G-3-P) to dihydroxyacetone phosphate (DHAP) with concomitant reduction of the enzyme-bound FAD. Together with a cytosolic NAD-linked GPD (GPD1; MIM 138420), GPD2 forms the glycerol phosphate shuttle, which uses the interconversion of G-3-P and DHAP to transfer reducing equivalents into mitochondria, resulting in the reoxidation of NADH formed during glycolysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FAD-linked glycerol-3-phosphate dehydrogenase; glycerol phosphate dehydrogenase 1, mitochondrial; Glycerol-3-phosophate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2 (mitochondrial); glycerol-3-phosphate dehydrogenase 2 (mitochondrial) isoform GPD2_1; glycerol-3-phosphate dehydrogenase 2 (mitochondrial) isoform GPD2_2; glycerol-3-phosphate dehydrogenase 2, mitochondrial; Glycerol-3-phosphate dehydrogenase, mitochondrial; GPD-M; GPD3; GPDH-M; mGDH; mitochondrial glycerol-3-phosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase; mitochondrial glycerophosphate dehydrogenase gene; mitohondrial glycerophosphate dehydrogenase; mtGPD; mtGPDH gene, promoter region and alternative transcripts; Protein TISP38; testicular tissue protein Li 76; unnamed protein product
Gene Aliases: AA408484; AI448216; AU021455; AW494132; GDH2; Gdm1; Gpd-m; GPD2; GPDH; Gpdh-m; GPDM; mGDH; mGPDH; mtGPDH; TISP38
UniProt ID: (Human) P43304, (Mouse) Q64521, (Rat) P35571
Entrez Gene ID: (Human) 2820, (Mouse) 14571, (Rat) 25062
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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