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Invitrogen

GSTP1 Polyclonal Antibody

Advanced Verification
1 Published Figure
3 References
View all (43) GSTP1 antibodies

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Product Details

PA5-29558

Applications
Tested Dilution
Publications

Western Blot (WB)

1:500-1:10,000
View 3 publications 3 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:1,000
-

Immunohistochemistry (Frozen) (IHC (F))

Assay-dependent
-

Immunocytochemistry (ICC/IF)

1:100-1:1,000
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human GSTP1. The exact sequence is proprietary.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.64 mg/mL

Amount

64 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7, with 20% glycerol

Contains

0.025% ProClin 300

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2547034

Product Specific Information

Recommended positive controls: A549, HCT116, Mouse brain, Rat brain.

Predicted reactivity: Mouse (85%), Rat (85%), Dog (86%), Rhesus Monkey (97%), Bovine (85%).

Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Target Information

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: Chain 7; deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; Glutathione S-transferase P; Glutathione S-transferase P 1; glutathione S-transferase pi 2; glutathione S-transferase, pi 2; Glutathione-S-transferase placental enzyme pi type; glutathione-S-transferase, pi 1; Glutathione-S-transferase, placental enzyme pi type; GST 7-7; GST class-pi; Gst p-1; Gst P1; GST YF-YF; GST-piB; GSTP1; GSTP1-1; HGNC:4638; Preadipocyte growth factor; unnamed protein product

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Gene Aliases: DFN7; FAEES3; GST-P; GST3; GSTP; GSTP1; Gstp2; GstpiB; HEL-S-22; PI

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UniProt ID: (Human) P09211, (Rat) P04906, (Mouse) P19157

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Entrez Gene ID: (Human) 2950, (Rat) 24426, (Mouse) 14870

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Function(s)
glutathione transferase activity glutathione peroxidase activity fatty acid binding protein binding JUN kinase binding toxic substance binding transferase activity protein kinase binding protein serine/threonine kinase inhibitor activity S-nitrosoglutathione binding dinitrosyl-iron complex binding nitric oxide binding drug binding kinase regulator activity glutathione binding transferase
Process(es)
negative regulation of transcription from RNA polymerase II promoter response to reactive oxygen species negative regulation of acute inflammatory response lipid metabolic process prostaglandin metabolic process glutathione metabolic process xenobiotic metabolic process central nervous system development response to toxic substance negative regulation of tumor necrosis factor-mediated signaling pathway oligodendrocyte development organ regeneration response to nutrient levels response to estradiol negative regulation of interleukin-1 beta production negative regulation of tumor necrosis factor production cellular response to insulin stimulus regulation of stress-activated MAPK cascade negative regulation of stress-activated MAPK cascade positive regulation of superoxide anion generation response to L-ascorbic acid common myeloid progenitor cell proliferation nitric oxide storage negative regulation of apoptotic process negative regulation of I-kappaB kinase/NF-kappaB signaling response to amino acid negative regulation of MAPK cascade linoleic acid metabolic process response to ethanol negative regulation of JNK cascade negative regulation of fibroblast proliferation hepoxilin biosynthetic process regulation of ERK1 and ERK2 cascade negative regulation of ERK1 and ERK2 cascade negative regulation of leukocyte proliferation cellular response to lipopolysaccharide cellular response to epidermal growth factor stimulus cellular response to glucocorticoid stimulus cellular response to cell-matrix adhesion negative regulation of monocyte chemotactic protein-1 production negative regulation of smooth muscle cell chemotaxis cellular oxidant detoxification glutathione derivative biosynthetic process negative regulation of vascular smooth muscle cell proliferation negative regulation of extrinsic apoptotic signaling pathway negative regulation of protein kinase activity negative regulation of biosynthetic process negative regulation of MAP kinase activity negative regulation of JUN kinase activity response to mercury ion negative regulation of nitric-oxide synthase biosynthetic process negative regulation of peroxidase activity metabolic process negative regulation of neutrophil aggregation
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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