Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
GSTP1 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
Product Details
PA5-96395
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human GST3/GST3/GSTP1 (NP_0008431)
Conjugate
Form
Liquid
Concentration
0.92 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2808197
Product Specific Information
Immunogen sequence: MPPYTVVYFP VRGRCAALRM LLADQGQSWK EEVVTVETWQ EGSLKASCLY GQLPKFQDGD LTLYQSNTIL RHLGRTLGLY GKDQQEAALV DMVNDGVEDL RCKYISLIYT NYEAGKDDYV KALPGQLKPF ETLLSQNQGG KTFIVGDQIS FADYNLLDLL LIHEVLAPGC LDAFPLLSAY VGRLSARPKL KAFLASPEYV NLPINGNGKQ; Positive Samples: SW620, HL-60, HT-29, 293T, U-251MG, Mouse kidney; Cellular Location: Cytoplasm, Mitochondrion, Nucleus
Target Information
Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: deafness, X-linked 7; epididymis secretory protein Li 22; fatty acid ethyl ester synthase III; Glutathione S-transferase P; Glutathione S-transferase P 1; GST class-pi; Gst p-1; Gst P1; GST YF-YF; GST-piB; GSTP1-1; HGNC:4638; Preadipocyte growth factor
Gene Aliases: DFN7; FAEES3; GST3; GSTP; GSTP1; GstpiB; HEL-S-22; PI
UniProt ID: (Human) P09211, (Mouse) P19157
Entrez Gene ID: (Human) 2950, (Mouse) 14870
response to reactive oxygen species
negative regulation of acute inflammatory response
negative regulation of protein kinase activity
glutathione metabolic process
xenobiotic metabolic process
central nervous system development
negative regulation of biosynthetic process
negative regulation of tumor necrosis factor-mediated signaling pathway
oligodendrocyte development
organ regeneration
response to estradiol
negative regulation of interleukin-1 beta production
negative regulation of tumor necrosis factor production
cellular response to insulin stimulus
regulation of stress-activated MAPK cascade
negative regulation of stress-activated MAPK cascade
positive regulation of superoxide anion generation
response to L-ascorbic acid
common myeloid progenitor cell proliferation
nitric oxide storage
negative regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
response to amino acid
negative regulation of MAP kinase activity
negative regulation of MAPK cascade
negative regulation of JUN kinase activity
linoleic acid metabolic process
response to ethanol
response to mercury ion
negative regulation of fibroblast proliferation
negative regulation of nitric-oxide synthase biosynthetic process
regulation of ERK1 and ERK2 cascade
negative regulation of ERK1 and ERK2 cascade
negative regulation of leukocyte proliferation
cellular response to lipopolysaccharide
cellular response to epidermal growth factor stimulus
cellular response to glucocorticoid stimulus
cellular response to cell-matrix adhesion
negative regulation of monocyte chemotactic protein-1 production
cellular oxidant detoxification
glutathione derivative biosynthetic process
negative regulation of extrinsic apoptotic signaling pathway
metabolic process
negative regulation of neutrophil aggregation
negative regulation of peroxidase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support