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Invitrogen
Galectin 1 Polyclonal Antibody
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FIGURE: 1 / 4
Galectin 1 Antibody (42-5900) in ICC/IF
Immunofluorescence analysis of Galectin 1 was performed using 70% confluent log phase MDA-MB-231 and MCF7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Galectin 1 Polyclonal Antibody (Product # 42-5900) at 1:100 in 0.1% BSA, incubated at 4 degre... View More
Product Details
42-5900
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the N-terminal region of the human galectin 1 protein.
Conjugate
Form
Liquid
Concentration
0.25 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.1% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
Galectin-1 belongs to a large family of carbohydrate-binding proteins called lectins. Galectin-1can be either monomeric or homodimeric and is found in a wide variety of cells and tissue types. Galectin-1 can control cell growth, proliferation, induce apoptosis of activated T cells while it can also modulate cytokine secretion or inhibit pro-inflammatory cytokine production. Galectin-1 plays an important role in acute and chronic inflammation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 14 kDa laminin-binding protein; 14 kDa lectin; beta-galactoside binding protein; Beta-galactoside-binding lectin L-14-I; beta-galactoside-binding protein 14kDa; DKFZp686E23103; epididymis secretory sperm binding protein; Gal-1; Galaptin; Galectin-1; Galectin1; H-Galectin-1; HBL; HLBP14; HPL; Lactose-binding lectin 1; Lectin galactoside-binding soluble 1; lectin precursor; lectin, galactoside-binding, soluble, 1; LGALS1; pm12; Putative MAPK-activating protein PM12; S-Lac lectin 1; unnamed protein product
Gene Aliases: AA410090; Gal-1; GAL1; Galbp; galectin-1; GBP; L-14.5; L14; Lect14; LGALS1
UniProt ID: (Human) P09382, (Mouse) P16045
Entrez Gene ID: (Human) 3956, (Mouse) 16852
plasma cell differentiation
apoptotic process
signal transduction
T cell costimulation
regulation of apoptotic process
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
myoblast differentiation
positive regulation of viral entry into host cell
positive regulation of inflammatory response
cell-cell adhesion
negative regulation of T-helper 17 cell lineage commitment
positive regulation of dendritic cell differentiation
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
negative regulation of cell-substrate adhesion
negative regulation of neuron projection development
positive regulation of erythrocyte aggregation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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