Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 14 publications 14 publications |
Immunohistochemistry (IHC) |
- | View 4 publications 4 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | View 1 publication 1 publication |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
ChIP assay (ChIP) |
Assay-dependent | View 1 publication 1 publication |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
HEY2 Fusion Protein Ag0913 (1-337 aa encoded by BC007707) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
This antibody is a rabbit polyclonal antibody raised against full length of human HEY2.
Immunogen sequence: MKRPCEETT SESDMDETID VGSENNYSGQ STSSVIRLNS PTTTSQIMAR KKRRGIIEKR RRDRINNSLS ELRRLVPTAF EKQGSAKLEK AEILQMTVDH LKMLQATGGK GYFDAHALAM DFMSIGFREC LTEVARYLSS VEGLDSSDPL RVRLVSHLST CATQREAAAM TSSMAHHHHP LHPHHWAAAF HHLPAALLQP NGLHASESTP CRLSTTSEVP PAHGSALLTA TFAHADSALR MPSTGSVAPC VPPLSTSLLS LSATVHAAAA AATAAAHSFP LSFAGAFPML PPNAAAAVAA ATAISPPLSV SATSSPQQTS SGTNNKPYRP WGTEVGAF (1-337 aa encoded by BC007707)
Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: bHLHb32; cardiovascular basic helix-loop-helix factor 1; Cardiovascular helix-loop-helix factor 1; Class B basic helix-loop-helix protein 32; h hHRT2; hairy and enhancer of split related 2; Hairy and enhancer of split-related protein 2; Hairy-E(spl)-related with YRPW motif 2; Hairy-related transcription factor 2; hairy/enhancer-of-split related with YRPW motif 2; Hairy/enhancer-of-split related with YRPW motif protein 2; hCHF1; hes-related family bHLH transcription factor with YRPW motif 2; HES-related repressor protein 1; HES-related repressor protein 2; HESR-2; hHRT2; HRT-2; mHRT2; Protein gridlock homolog
Gene Aliases: BHLHB32; CHF1; GRIDLOCK; GRL; HERP; HERP1; HESR2; HEY2; HRT2
UniProt ID: (Human) Q9UBP5, (Mouse) Q9QUS4
Entrez Gene ID: (Human) 23493, (Mouse) 15214
Molecular Function:
basic helix-loop-helix transcription factor
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