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Invitrogen
IL-4 Polyclonal Antibody
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Product Details
PBOIL4I
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine
Published species
Bovine
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant bovine IL-4
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
1 mg/mL
Amount
1 mg
Purification
Protein G
Storage buffer
PBS
Contains
no preservative
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PBOIL4I targets IL-4 in ELISA, and WB applications and shows reactivity with Bovine samples.
The PBOIL4I immunogen is recombinant bovine IL-4.
PBOIL4I detects IL-4 which has a predicted molecular weight of approximately 13 kDa.
Endotoxin levels are less than or equal to 10 µg/mL.
Target Information
Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play an important role in mediating the immune regulatory signal of IL-4. The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. In particular, IL-4 is located in close proximity to IL13 on the chromosome. Further, the IL-4 gene, IL13 and IL5 are found to be coordinated by several long-range regulatory elements over a 120 kilobase range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: B-cell stimulatory factor 1; H-IL-4; ILN; Interleukin; Interleukin4; lymphocyte stimulatory factor 1; M-IL-4; MGC79402
Gene Aliases: BSF-1; IL-4
UniProt ID: (Bovine) P30367
Entrez Gene ID: (Bovine) 280824
positive regulation of macroautophagy
positive regulation of B cell proliferation
positive regulation of T cell proliferation
B cell activation
regulation of phosphorylation
negative regulation of apoptotic process
positive regulation of MHC class II biosynthetic process
negative regulation of osteoclast differentiation
negative regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of isotype switching to IgE isotypes
positive regulation of isotype switching to IgG isotypes
regulation of immune response
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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