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Abnova
IQWD1 Polyclonal Antibody, MaxPab™
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Product Details
H00055827-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
IQWD1 (AAH25262.1, 1 a.a. approximately 513 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MLSRWFEEAS EVAQSNRGRG RSRPRGGTSQ SDISTLPTVP SSPDLEVSET AMEVDTPAEQ FLQPSTSSTM SAQAHSTSSP TESPHSTPLL SSPDSEQRQS VEASGHHTHH QSDNNNEKLS PKPGTGEPVL SLHYSTEGTT TSTIKLNFTD EWSSIASSSR GIGSHCKSEG QEESFVPQSS VQPPEGDSET KAPEESSEDA TKYQEGVSAE NPVENHINIT QSDKFTAKPL DSNSGERNDL NLDRSCGVPE ESASSEKAKE PETSDQTSTE SATNENNTNP EPQFQTEATG PSAHEETSTR DSALQDTDDS DDDPVLIPGA RYRAGPGDRR SAVARIQEFF RRRKERKEME ELDTLNIRRP LVKMVYKGHR NSRTMIKEAN FWGANFVMSG SDCGHIFIWD RHTAEHLMLL EADNHVVNCL QPHPFDPILA SSGIDYDIKI WSPLEESRIF NRKLADEVIT RNELMLEETR NTITVPASFM LRMLASLNHI RADRLEGDRS EGSGQENENE DEE
Target Information
NRIP is a novel 860a.a nuclear protein consisting of seven conserved WD40 domains and one NLS motif. It binds to androgen and glucocorticoid receptors and up regulates their transcriptional activity, thereby functioning as a nuclear receptor coactivator. Role of NRIP has been implicated in cell growth and also in cervical and prostrate cancer thus indicating a therapeutic intervention. Northern Blot analysis detected a high expression of NRIP in skeletal muscle and testis and low expression in heart, prostrate and adrenal gland.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Androgen receptor complex-associated protein; ARCAP; DDB1- and CUL4-associated factor 6; IQ motif and WD repeat-containing protein 1; IQ motif and WD repeats 1; NRIP; Nuclear receptor interaction protein
Gene Aliases: 1200006M05Rik; ARCAP; DCAF6; IQWD1; MSTP055; NRIP; PC326
UniProt ID: (Human) Q58WW2
Entrez Gene ID: (Human) 55827
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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