alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha3beta1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.
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Protein Aliases: alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; Beta OL; Beta oligodendroglia; CD29; CD49 antigen-like family member C; CD49c; Fibronectin receptor subunit beta; FRP-2; Galactoprotein B3; GAPB3; Glycoprotein IIa; GPIIA; integrin alpha 3; Integrin alpha-3; Integrin alpha-3 heavy chain; Integrin alpha-3 light chain; integrin beta 1; integrin beta 1 (fibronectin receptor beta); Integrin beta-1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); testicular tissue protein Li 96; testicular tissue protein Li 98; very late activation protein 3 receptor, alpha-3 subunit; very late activation protein, beta polypeptide; VLA-3 subunit alpha; VLA-4 subunit beta
Gene Aliases: 4633401G24Rik; AA407068; AA409975; AA960159; CD29; CD49C; ENSMUSG00000051907; FNRB; FRP-2; GAP-B3; GAPB3; Gm9863; GPIIA; ILNEB; ITGA3; ITGB1; MDF2; MSK12; MSK18; VCA-2; VL3A; VLA-BETA; VLA3a; VLAB