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          • Primary Antibodies ›
          • Integrin alpha 3/beta 1 Antibodies

          Bioss

          Integrin Alpha 3 + Beta 1 Polyclonal Antibody

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          Cite Integrin Alpha 3 + Beta 1 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (4)
          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.
          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          Integrin Alpha 3 + Beta 1 Antibody (BS-1057R) in ICC/IF

          Image provided by One World Lab validation program. MCF-7 cells probed with Rabbit Anti-Integrin Alpha 3 + Beta 1 Polyclonal Antibody (bs-1057R) at 1:50 for 60 minutes at room temperature followed by Goat Anti-Rabbit IgG (H+L) Alexa Fluor 488 Conjugated secondary antibody. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
          PMID: {{$ctrl.currentElement.benchSciPubmedId}}
          View Product

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          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Integrin Alpha 3 + Beta 1 Antibody in Immunocytochemistry (ICC/IF)
          Integrin Alpha 3 + Beta 1 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Integrin Alpha 3 + Beta 1 Antibody in Western Blot (WB)
          Integrin Alpha 3 + Beta 1 Polyclonal Antibody

          Product Details

          BS-1057R

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200
          -

          Immunohistochemistry (Frozen) (IHC (F))

          1:100-1:500
          -

          Immunocytochemistry (ICC/IF)

          1:50
          -

          Flow Cytometry (Flow)

          1:20-1:100
          -

          ELISA (ELISA)

          1:500-1:1,000
          -
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Mixed KLH conjugated synthetic peptide derived from human Integrin Alpha 3 (976-1025/1051) + Beta 1 (35-47/798).
          3D Epitope / Immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Amount

          100 µg

          Purification

          Protein A

          Storage buffer

          0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

          Contains

          0.02% ProClin 300

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          alpha3beta1 integrin is a laminin receptor with apparently diverse functions. In epithelial cells it acts as a receptor for the basement membrane, whereas in neuronal and possibly tumor cells it mediates migration. Interactions of alpha3beta1 integrin with tetraspanin proteins may provide clues to how it transduces signals that affect cell behavior.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: alpha 3 subunit of VLA-3 receptor; antigen CD49C; antigen identified by monoclonal antibody J143; Beta OL; Beta oligodendroglia; CD29; CD49 antigen-like family member C; CD49c; Fibronectin receptor subunit beta; FRP-2; Galactoprotein B3; GAPB3; Glycoprotein IIa; GPIIA; integrin alpha 3; Integrin alpha-3; integrin beta 1; integrin beta 1 (fibronectin receptor beta); Integrin beta-1; integrin beta-1 subunit (cytoplasmic domain); integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor); integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); testicular tissue protein Li 96; testicular tissue protein Li 98; unnamed protein product; very late activation protein 3 receptor, alpha-3 subunit; very late activation protein, beta polypeptide; very late activation receptor subunit alpha-3; VLA-3 subunit alpha; VLA-4 subunit beta

          View more View less

          Gene Aliases: 4633401G24Rik; AA407068; AA409975; AA960159; CD29; CD49C; ENSMUSG00000051907; FNRB; FRP-2; GAP-B3; GAPB3; Gm9863; GPIIA; ILNEB; ITGA3; ITGB1; JEB7; MDF2; MSK12; MSK18; VCA-2; VL3A; VLA-BETA; VLA3a; VLAB

          View more View less

          UniProt ID: (Human) P26006, (Human) P05556, (Mouse) Q62470, (Mouse) P09055, (Rat) P49134

          View more View less

          Entrez Gene ID: (Human) 3675, (Human) 3688, (Rat) 360606, (Mouse) 16400, (Mouse) 16412, (Rat) 24511

          View more View less

          Function(s)
          fibronectin binding protease binding integrin binding protein binding collagen binding protein domain specific binding signaling receptor activity laminin binding macromolecular complex binding metal ion binding protein heterodimerization activity magnesium ion binding virus receptor activity actin binding calcium ion binding coreceptor activity protein kinase binding C-X3-C chemokine binding cadherin binding cell adhesion molecule binding collagen binding involved in cell-matrix adhesion integrin binding involved in cell-matrix adhesion protein tyrosine kinase binding glycoprotein binding receptor activity receptor binding kinase binding protein complex binding peptide binding alpha-actinin binding integrin
          Process(es)
          neuron migration system process cell adhesion cell-matrix adhesion integrin-mediated signaling pathway Rho protein signal transduction heart development memory response to xenobiotic stimulus regulation of signal transduction positive regulation of gene expression positive regulation of epithelial cell migration positive regulation of cell-substrate adhesion positive regulation of neuron projection development regulation of transforming growth factor beta receptor signaling pathway regulation of Wnt signaling pathway cell differentiation lung development regulation of BMP signaling pathway negative regulation of cell projection organization response to gonadotropin negative regulation of Rho protein signal transduction exploration behavior skin development mesodermal cell differentiation system development leukocyte migration maternal process involved in female pregnancy nephron development dendritic spine maintenance renal filtration cell-cell adhesion postsynapse organization synaptic membrane adhesion positive regulation of protein localization to plasma membrane G1/S transition of mitotic cell cycle establishment of mitotic spindle orientation angiogenesis in utero embryonic development cell migration involved in sprouting angiogenesis positive regulation of neuroblast proliferation phagocytosis cellular defense response homophilic cell adhesion via plasma membrane adhesion molecules leukocyte cell-cell adhesion calcium-independent cell-matrix adhesion transforming growth factor beta receptor signaling pathway neuroblast proliferation muscle organ development myoblast fusion cell proliferation germ cell migration visual learning regulation of collagen catabolic process positive regulation of fibroblast migration response to muscle activity cell migration formation of radial glial scaffolds central nervous system neuron differentiation CD40 signaling pathway cell projection organization lamellipodium assembly B cell differentiation extracellular matrix organization positive regulation of cell migration neuron projection development cell-substrate adhesion receptor internalization cell adhesion mediated by integrin cell-cell adhesion mediated by integrin heterotypic cell-cell adhesion wound healing, spreading of epidermal cells maintenance of blood-brain barrier positive regulation of apoptotic process stress fiber assembly positive regulation of GTPase activity sarcomere organization myoblast differentiation negative regulation of neuron differentiation positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of angiogenesis negative regulation of vasoconstriction viral entry into host cell myoblast fate specification axon extension dendrite morphogenesis regulation of developmental process modulation of synaptic transmission leukocyte tethering or rolling regulation of cell cycle positive regulation of protein kinase B signaling positive regulation of glutamate uptake involved in transmission of nerve impulse cardiac muscle cell differentiation cardiac muscle cell myoblast differentiation cardiac cell fate specification regulation of biological quality cellular response to low-density lipoprotein particle stimulus basement membrane organization positive regulation of wound healing regulation of spontaneous synaptic transmission reactive gliosis positive regulation of vascular endothelial growth factor signaling pathway regulation of synapse pruning negative regulation of anoikis fusion of sperm to egg plasma membrane response to drug single-organism behavior positive regulation of establishment of protein localization to plasma membrane cell fate specification tissue homeostasis cellular calcium ion homeostasis regulation of G-protein coupled receptor protein signaling pathway positive regulation of cell proliferation negative regulation of cell proliferation protein transport within lipid bilayer positive regulation of MAPK cascade negative regulation of cell differentiation positive regulation of neuron differentiation positive regulation of endocytosis cardiac muscle tissue development positive regulation of peptidyl-tyrosine phosphorylation bicellular tight junction assembly response to activity response to nutrient levels cellular response to mechanical stimulus cellular response to vitamin D cellular response to ionizing radiation response to transforming growth factor beta
          It has to be done as per old AB suggested Products section.

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