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Proteintech
Integrin alpha-8 Polyclonal Antibody
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Product Details
30714-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Integrin alpha-8 fusion protein Ag33507
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
60 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: GVSHPPQIVL PIHNWEPEEE PHKEEEVGPL VEHIYELHNI GPSTISDTIL EVGWPFSARD EFLLYIFHIQ TLGPLQCQPN PNINPQDIKP AASPEDTPEL SAFLRNSTIP HLVRKRDVHV VEFHRQSPAK ILNCTNIECL QISCAVGRLE GGESAVLKVR SRLWAHTFLQ RKNDPYALAS
Target Information
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Integrin alpha-8; integrin, alpha 8; unnamed protein product
Gene Aliases: AI447669; ITGA8; RGD1564327
UniProt ID: (Human) P53708, (Mouse) A2ARA8
Entrez Gene ID: (Human) 8516, (Mouse) 241226, (Rat) 364786
metanephros development
formation of primary germ layer
kidney development
cell adhesion
cell-matrix adhesion
transforming growth factor beta receptor signaling pathway
integrin-mediated signaling pathway
nervous system development
memory
tissue development
cell projection organization
cell differentiation
extracellular matrix organization
positive regulation of transforming growth factor beta receptor signaling pathway
cell-substrate adhesion
substrate adhesion-dependent cell spreading
inner ear morphogenesis
establishment of protein localization
positive regulation of transcription from RNA polymerase II promoter
mesodermal cell differentiation
smooth muscle tissue development
smooth muscle cell differentiation
cell-cell adhesion
multicellular organism development
positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation
brain development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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