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Product Details
20150-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
LGR4 Fusion Protein Ag13695 (27-376 aa encoded by BC033039)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: PLCAAPCSC DGDRRVDCSG KGLTAVPEGL SAFTQALQLA GNDLSFIHPK ALSGLKELKV LTLQNNQLKT VPSEAIRGLS ALQSLRLDAN HITSVPEDSF EGLVQLRHLW LDDNSLTEVP VHHLSNLPTL QALTLALNKI SSIPDFAFTN LSSLVVLHLH NNKIRSLSQH CFDGLDNLET LDLNYNNLGE FPQAIKALPS LKELGFHSNS ISVIPDGAFD GNPLLRTIHL YDNPLSFVGN SAFHNLSDLH SLVIRGASMV QQFPNLTGTV HLESLTLTGT KISSIPNNLC QEQKMLRTLD LSYNNIRDLP SFNGCHALEE ISLQRNQIYQ IKEGTFQGLI SLRILDLSRN L (27-376 aa encoded by BC033039)
Target Information
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR LGR4 is a member of this family (subfamily Orphan-A). Its expression has been documented in human brain, adrenal, heart, kidney, liver, skeletal muscle, ovary, pancreas, placenta, prostate, spleen, stomach, testis, thyroid, and spinal cord.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: G protein-coupled receptor 48; G protein-coupled receptor GPR48; G-protein coupled receptor 48; leucine-rich repeat containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4
Gene Aliases: 9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; GPR48; LGR4
UniProt ID: (Human) Q9BXB1, (Mouse) A2ARI4, (Rat) Q9Z2H4
Entrez Gene ID: (Human) 55366, (Mouse) 107515, (Rat) 286994
osteoblast differentiation
hair follicle development
G-protein coupled receptor signaling pathway
spermatogenesis
bone mineralization
male genitalia development
circadian regulation of gene expression
negative regulation of toll-like receptor signaling pathway
intestinal stem cell homeostasis
innate immune response
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
bone remodeling
digestive tract development
negative regulation of cytokine secretion
canonical Wnt signaling pathway involved in metanephric kidney development
cell differentiation involved in metanephros development
metanephric glomerulus development
metanephric nephron tubule morphogenesis
positive regulation of branching involved in ureteric bud morphogenesis
positive regulation of canonical Wnt signaling pathway
epithelial cell proliferation involved in renal tubule morphogenesis
immune system process
signal transduction
multicellular organism development
Wnt signaling pathway
cell differentiation
tube morphogenesis
rhythmic process
epithelial cell proliferation
biological_process
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