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Immunogen sequence: EHIHMDNLAQ MPMISIPRVE SPLEKVTSVQ NHITAFAEVT
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 70%.
The protein encoded by this gene is a type 2 member of the phosphatidic acid phosphatase (PAP) family. All type 2 members of this protein family contain 6 transmembrane regions, and a consensus N-glycosylation site. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Induces filopodia formation and promotes neurite growth in a CDC42-independent manner; impedes neurite growth inhibitory-mediated axonal retraction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Lipid phosphate phosphatase-related protein type 5; phosphatidic acid phosphatase 2d; phosphatidic acid phosphatase type 2; Phosphatidic acid phosphatase type 2d; Phospholipid phosphatase-related protein type 5; Plasticity-related gene 5 protein; plasticity-related protein 5; PRG-5
Gene Aliases: LPPR5; PAP2; PAP2D; PLPPR5; PRG5
UniProt ID: (Human) Q32ZL2
Entrez Gene ID: (Human) 163404
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