Applications | Tested Dilution | Publications |
---|---|---|
Immunocytochemistry (ICC/IF) |
0.25-2 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human LRRC17 |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2926917 |
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: DYNIHYLYYW LKHHYNVHFN GLECKTPEEY KGWSVGKYIR SYYEECPKDK LPAYPESFDQ DTEDDEWEKK HRDHTAKKQS VII
Leucine-rich repeat-containing protein 17 (LRRC17) is an LRR protein predominantly expressed by osteoblasts. LRRC17 acts as a negative regulator of receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation. It has been reported that low plasma level of LRRC17 is an independent risk factor for osteoporotic fractures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 37 kDa leucine-rich repeat (LRR) protein; Leucine-rich repeat-containing protein 17; p37NB
Gene Aliases: LRRC17; P37NB; UNQ3076/PRO9909
UniProt ID: (Human) Q8N6Y2
Entrez Gene ID: (Human) 10234
Molecular Function:
transmembrane signal receptor
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