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Invitrogen
Laminin beta-2/gamma-1 Monoclonal Antibody (A5), Biotin
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-14646
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Mouse,
Rat,
Rhesus monkey
Host/Isotype
Rat
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
A5
Immunogen
Murine EHS laminin preparation
Conjugate
Biotin
Biotin
Biotin
Form
Liquid
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Protein G
Storage buffer
PBS, pH 7.4, with 0.2% BSA
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
MA5-14646 targets Laminin B2/gamma1 in IF, IHC (F), IHC (P, F), and IP applications and shows reactivity with Human and mouse samples.
The MA5-14646 immunogen is mouse EHS laminin preparation.
Target Information
Laminins are large heterotrimeric, noncollagenous glycoproteins composed of alpha, beta, and gamma chains. They are ubiquitously present in basement membrane (BM) along with entactin/nidogen (EN), collagen type IV (CIV), and large heparan sulfate proteoglycan (HSPG), which interact specifically with each other to form a continuous and regular BM. Alterations of BM integrity, from local discontinuities up to complete loss, are described in many types of human and animal epithelial neoplasms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: AA408497; Lama; laminin B1s chain; laminin B2 chain; laminin B2 precursor; Laminin S; laminin, beta 2 (laminin S); laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; laminin-10 subunit gamma; laminin-11 subunit beta; laminin-11 subunit gamma; laminin-14 subunit beta; laminin-15 subunit beta; laminin-2 subunit gamma; laminin-3 subunit beta; laminin-3 subunit gamma; laminin-4 subunit beta; laminin-4 subunit gamma; laminin-6 subunit gamma; laminin-7 subunit beta; laminin-7 subunit gamma; laminin-8 subunit gamma; laminin-9 subunit beta; laminin-9 subunit gamma; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma; unnamed protein product
Gene Aliases: Lamb-2; LAMB2; LAMS; NPHS5; npht; PIERS
UniProt ID: (Human) P55268, (Human) P11047, (Mouse) Q61292
Entrez Gene ID: (Human) 3913, (Human) 3915, (Mouse) 16779, (Mouse) 226519
cell morphogenesis
axon guidance
neuromuscular junction development
visual perception
organ morphogenesis
tissue development
astrocyte development
Schwann cell development
cell migration
neuron projection development
substrate adhesion-dependent cell spreading
positive regulation of cell adhesion
axon extension involved in regeneration
synapse organization
positive regulation of muscle cell differentiation
retina development in camera-type eye
basement membrane assembly
metanephric glomerular visceral epithelial cell development
metanephric glomerular basement membrane development
regulation of basement membrane organization
positive regulation of integrin-mediated signaling pathway
chromatin organization
cell adhesion
signal transduction
gene expression
extracellular matrix disassembly
hair follicle morphogenesis
hemidesmosome assembly
hair cell differentiation
tissue morphogenesis
protein-containing complex assembly
hair follicle cell proliferation
positive regulation of skeletal muscle acetylcholine-gated channel clustering
endoderm development
regulation of cell adhesion
regulation of cell migration
maintenance of blood-brain barrier
regulation of embryonic development
positive regulation of epithelial cell proliferation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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