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Invitrogen
CD4 alpha Monoclonal Antibody (MIL17)
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FIGURE: 1 / 1
CD4 alpha Antibody (MA5-28363) in Flow
Flow cytometry of CD4 alpha in red cell lysed porcine blood. Sample was incubated with CD4 alpha monoclonal antibody (Product # MA5-28363) and gated on lymphocytes. Figures are arranged as follows: A) RPE conjugated mouse anti porcine CD45a antibody, clone MIL17 and FITC conjugated mouse IgM isotype control. B) RPE conjugated mouse anti porcine CD45a and FITC conjugated mouse anti porcine CD4.
Product Details
MA5-28363
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Pig
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
MIL17
Immunogen
Leucocytes isolated from porcine gut lamina propria
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody recognizes approximately a 55 kDa porcine homologue to the human CD4 antigen found on the surface of helper-T cells.
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene [RefSeq, July 2017].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD4; CD4 antigen p55; cd4a; fCD4; Leu-3; lymphocyte antigen CD4
Entrez Gene ID: (Pig) 404704
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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