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Proteintech
MEIS3 Polyclonal Antibody
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Product Details
12775-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MEIS3 Fusion Protein Ag3471 (76-421 aa encoded by BC025404)
Conjugate
Form
Liquid
Concentration
0.41 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CELATCSPR DGAGAGLGTP PGGDVCSSDS FNEDIAAFAK QVRSERPLFS SNPELDNLMI QAIQVLRFHL LELEKVHDLC DNFCHRYITC LKGKMPIDLV IEDRDGGCRE DFEDYPASCP SLPDQNNMWI RDHEDSGSVH LGTPGPSSGG LASQSGDNSS DQGDGLDTSV ASPSSGGEDE DLDQERRRNK KRGIFPKVAT NIMRAWLFQH LSRRSEAPVL PDVCLGLGSP SPGPRWARPW GSDCGRPGRQ SDSCWWLQHP YPSEEQKKQL AQDTGLTILQ VNNWFINARR RIVQPMIDQS NRTGQGAAFS PEGQPIGGYT ETQPHVAVRP PGSVGMSLNL EGEWHYL (76-421 aa encoded by BC025404)
Target Information
Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Homeobox protein Meis3; Meis1, myeloid ecotropic viral integration site 1 homolog 3; Meis1-related protein 2; myeloid ecotropic viral integration site-related gene 2; unnamed protein product
Gene Aliases: AI573393; MEIS3; MRG2
UniProt ID: (Human) Q99687, (Mouse) P97368
Entrez Gene ID: (Human) 56917, (Rat) 361514, (Mouse) 17537
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
sequence-specific DNA binding
sequence-specific double-stranded DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
chromatin binding
homeodomain transcription factor
angiogenesis
eye development
regulation of transcription, DNA-templated
brain development
positive regulation of cell proliferation
embryonic pattern specification
organ morphogenesis
hemopoiesis
positive regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of protein kinase B signaling
negative regulation of apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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