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Product Details
18939-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Not Applicable
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MIDN Fusion Protein Ag13492 (127-468 aa encoded by BC094778)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: TQVSDFLSG RSPLTLALRV GDHMMFVQLQ LAAQHAPLQH RHVLAAAAAA AAARGDPSIA SPVSSPCRPV SSAARVPPVP TSPSPASPSP ITAGSFRSHA ASTTCPEQMD CSPTASSSAS PGASTTSTPG ASPAPRSRKP GAVIESFVNH APGVFSGTFS GTLHPNCQDS SGRPRRDIGT ILQILNDLLS ATRHYQGMPP SLAQLRCHAQ CSPASPAPDL APRTTSCEKL TAAPSASLLQ GQSQIRMCKP PGDRLRQTEN RATRCKVERL QLLLQQKRLR RKARRDARGP YHWSPSRKAG RSDSSSSGGG GSPSEASGLG LDFEDSVWKP EANPDIKSEF VVA (127-468 aa encoded by BC094778)
Target Information
Expression of the midnolin gene is developmentally regulated: it is strongly expressed at the mesencephalon (midbrain) of the embryo in day 12.5 (E12.5) mice. The midnolin encodes a protein of 508 amino acids (aa), which contains a Ubiquitin-like domain. The intracellular distribution of the midnolin was studied by using midnolin-green fluorescent protein (GFP) fusion proteins. Midnolin was found to be localized in the nucleus and nucleolus, but not in the cytoplasm. The nucleolar localization signal was determined to be a 28aa peptide located at the C-terminal region of the midnolin. May be involved in regulation of genes related to neurogenesis in the nucleolus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DKFZp547M072; Midbrain nucleolar protein; Midnolin
Gene Aliases: 3000003C15Rik; MIDN
UniProt ID: (Human) Q504T8, (Rat) D4AE48, (Mouse) Q3TPJ7
Entrez Gene ID: (Human) 90007, (Rat) 314623, (Mouse) 59090
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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