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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • MOS Antibodies

          Invitrogen

          MOS Polyclonal Antibody

          View all (8) MOS antibodies

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          Cite MOS Polyclonal Antibody

          • Antibody Testing Data (1)
          MOS Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          MOS Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          MOS Antibody (PA5-44590) in WB

          Western blot analysis of human NCI-H226 cell lysate using an anti-MOS polyclonal antibody (Product # PA5-44590). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          MOS Antibody in Western Blot (WB)

          Product Details

          PA5-44590

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.2-1 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthetic peptide directed towards the middle region of human MOS

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.5 mg/mL

          Purification

          Affinity Chromatography

          Storage buffer

          PBS with 2% sucrose

          Contains

          0.09% sodium azide

          Storage conditions

          -20°C, Avoid Freeze/Thaw Cycles

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2609843

          Product Specific Information

          Peptide sequence: LNVARLRHDN IVRVVAASTR TPAGSNSLGT IIMEFGGNVT LHQVIYGAAG

          Sequence homology: Cow: 92%; Dog: 100%; Guinea Pig: 86%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%

          Target Information

          Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: c-mos; MGC119962; MGC119963; oncogene MOS, Moloney murine sarcoma virus; Oocyte maturation factor mos; Proto-oncogene c-Mos; Proto-oncogene serine/threonine-protein kinase mos

          View more View less

          Gene Aliases: MOS; MSV

          View more View less

          UniProt ID: (Human) P00540

          View more View less

          Entrez Gene ID: (Human) 4342

          View more View less

          Function(s)
          protein serine/threonine kinase activity MAP kinase kinase kinase activity protein binding ATP binding non-receptor serine/threonine protein kinase
          Process(es)
          MAPK cascade activation of MAPKK activity activation of MAPK activity meiotic spindle organization chromatin organization protein autophosphorylation establishment of meiotic spindle orientation negative regulation of metaphase/anaphase transition of meiotic cell cycle
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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