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Proteintech
MSN Polyclonal Antibody
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Product Details
26053-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
MSN Fusion Protein Ag23531 (385-502 aa encoded by BC017293)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody does not react with talin or ezrin. It weakly reacts with radixin. It detects most of the proteolytic fragments of moesin.
Immunogen sequence: EAEKLAKER QEAEEAKEAL LQASRDQKKT QEQLALEMAE LTARISQLEM ARQKKESEAV EWQQKAQMVQ EDLEKTRAEL KTAMSTPHVA EPAENEQDEQ DENGAEASAD LRADAMAKD (385-502 aa encoded by BC017293)
Target Information
Moesin, a member of the talin-4. 1 superfamily, is a linking protein of the submembraneous actin cytoskeleton. It is expressed in macrophages, lymphocytes, fibroblastic, endothelial, epithelial, and neuronal cell lines but not in blood cells. It is involved in cell adhesion, migration, and organization of cell surface structures.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis luminal protein 70; Membrane-organizing extension spike protein; Moesin; unnamed protein product
Gene Aliases: HEL70; IMD50; MSN
UniProt ID: (Human) P26038
Entrez Gene ID: (Human) 4478
immunological synapse formation
cytoskeleton organization
leukocyte cell-cell adhesion
regulation of cell shape
regulation of cell size
positive regulation of gene expression
gland morphogenesis
membrane to membrane docking
T cell proliferation
establishment of epithelial cell apical/basal polarity
positive regulation of protein catabolic process
leukocyte migration
establishment of endothelial barrier
T cell aggregation
positive regulation of podosome assembly
T cell migration
regulation of organelle assembly
positive regulation of protein localization to early endosome
regulation of lymphocyte migration
positive regulation of early endosome to late endosome transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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