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Proteintech
NEURL Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
18898-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NEURL Fusion Protein Ag13531 (1-345 aa encoded by BC026336)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.15 mg/mL
Amount
22.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to NEURL.
Immunogen sequence: MGNNFSSIP SLPRGNPSRA PRGHPQNLKD SIGGPFPVTS HRCHHKQKHC PAVLPSGGLP AAPLLFHPHT KGSQILMDLS HKAVKRQASF CNAITFSNRP VLIYEQVRLK ITKKQCCWSG ALRLGFTSKD PSRIHPDSLP KYACPDLVSQ SGFWAKALPE EFANEGNIIA FWVDKKGRVF HRINDSAVML FFSGVRTADP LWALVDVYGL TRGVQLLDSE LVLPDCLRPR SFTALRRPSL RREADDARLS VSLCDLNVPG ADGDEAAPAA SCPIPQNSLN SQHSRALPAQ LDGDLRFHAL RAGAHVRILD EQTVARVEHG RDERALVFTS RPVRVAETIF VKVTRS (1-345 aa encoded by B C026336)
Target Information
NEURL is involved in the determination of cell fate in the neurogenic region of the embryo and plays a role in the determination of cell fate in the central nervous system. NEURL may act as a tumor suppressor whose inactivation could be associated with malignant progression of astrocytic tumors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: h neu; h neuralized 1; h-neuralized 1; neuralized homolog; neuralized homolog 1A; neuralized-like homolog; neuralized-like protein 1A; ring finger protein; RING finger protein 67; RING-type E3 ubiquitin transferase NEURL1; unnamed protein product
Gene Aliases: bA416N2.1; neu; neu-1; NEUR1; NEURL; Neurl1a; RNF67
UniProt ID: (Human) O76050
Entrez Gene ID: (Human) 9148, (Rat) 309459
regulation of translation
protein monoubiquitination
skeletal muscle tissue development
negative regulation of cell proliferation
regulation of Notch signaling pathway
regulation of cell communication
regulation of signaling
positive regulation of apoptotic process
negative regulation of Notch signaling pathway
positive regulation of long-term neuronal synaptic plasticity
positive regulation of filopodium assembly
positive regulation of dendritic spine development
cellular response to amino acid stimulus
positive regulation of synapse maturation
regulation of postsynapse assembly
nervous system development
protein ubiquitination
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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