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Netrin 1 Polyclonal Antibody
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Product Details
X1870P
Product Specifications
Species Reactivity
Bovine,
Cat,
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide derived from the human Netrin 1 protein
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.5-2 mg/mL
Amount
25 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.08% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive control: Antibody tested on MDCKII cell lysates.
Target Information
Netrin-1 is a protein target that plays a crucial role in various biological processes, particularly in the development and guidance of neuronal cells. It belongs to the netrin family of axon guidance molecules and is involved in mediating axon guidance, cell migration, and tissue morphogenesis during embryonic development. Netrin-1 functions by binding to specific receptors on the cell surface and providing directional cues for cellular movement and connectivity. Dysregulation of Netrin-1 has been implicated in various diseases, including cancer, neurological disorders, and cardiovascular conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: epididymis tissue protein Li 131P; HGNC:8029; netrin 1, mouse, homolog of; Netrin1; tropic factor
Gene Aliases: MRMV4; NET1; Netrin-1; NTN1L
UniProt ID: (Human) O95631, (Mouse) O09118
Entrez Gene ID: (Human) 9423, (Bovine) 522767, (Mouse) 18208, (Rat) 114523
regulation of transcription from RNA polymerase II promoter
substrate-dependent cell migration, cell extension
Ras protein signal transduction
Cdc42 protein signal transduction
positive regulation of axon extension
regulation of synapse assembly
chemorepulsion of axon
positive regulation of cell motility
neuron migration
nuclear migration
axonogenesis
axon guidance
motor neuron axon guidance
positive regulation of cell proliferation
organ morphogenesis
tissue development
dendrite development
regulation of cell migration
negative regulation of axon extension
mammary gland development
anterior/posterior axon guidance
inner ear morphogenesis
mammary gland duct morphogenesis
cell-cell adhesion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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