PA1-32067 detects OSBPL2 from human samples.
PA1-32067 has been successfully used in ELISA and Western blot applications.
The PA1-32067 immunogen is: Peptide with sequence YFERNFSDCPDIY, from C Terminus of the protein sequence according to NP_055650; NP_653081
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
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Protein Aliases: FLJ20223; KIAA0772; MGC4307; MGC8342; ORP-2; ORP2; OSBP-related protein 2; oxysterol binding protein-like 2; oxysterol-binding protein-like 2; Oxysterol-binding protein-related protein 2
Gene Aliases: C130070J12Rik; DFNA67; DNFA67; KIAA0772; mKIAA0772; ORP-2; ORP2; OSBPL2