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P2RY1 Polyclonal Antibody
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Product Details
OSP00121W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Guinea pig,
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from the extracellular domain of human P2Y1 (P2RY1) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: P2RY1.
Target Information
P2Y1 is a Purinergic Receptor that causes a change in platelet shape and potentially leads to platelet aggregation by binding ADP, which results in the mobilization of intracellular calcium ions via activation of phospholipase C. This receptor also mediates the release of the relaxing factor nitric oxide and may be involved in the modulation of neuronal signal transmission. P2Y1 has been reported to be expressed in tissues throughout the body, particularly brain. ESTs have been isolated from human embryo, lung, and placenta libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: ADP receptor; ATP receptor; membrane protein; P2 purinoceptor subtype Y1; P2Y purinoceptor 1; p2y-1-r; P2Y1; P2Y1 purinoceptor; p2y1r; platelet ADP receptor; Purinergic receptor; purinergic receptor P2Y, G-protein coupled 1; purinergic receptor P2Y, G-protein coupled, 1; Purinoceptor p2y1; Purinoceptor p2yr1; suppressing androgen receptor in renal cell carcinoma; unnamed protein product
Gene Aliases: P2RY1; P2Y1; SARCC
UniProt ID: (Human) P47900, (Guinea pig) P59902
Entrez Gene ID: (Human) 5028, (Guinea pig) 100135592
nucleotide binding
ADP receptor activity
G-protein coupled receptor activity
protein binding
ATP binding
receptor regulator activity
A1 adenosine receptor binding
signaling receptor activity
ADP binding
G-protein coupled purinergic nucleotide receptor activity
ATP-activated adenosine receptor activity
protein heterodimerization activity
scaffold protein binding
G-protein coupled receptor
adenosine receptor signaling pathway
ion transport
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
blood coagulation
hemostasis
glial cell migration
regulation of cell shape
response to mechanical stimulus
negative regulation of norepinephrine secretion
signal transduction involved in regulation of gene expression
platelet activation
positive regulation of inositol trisphosphate biosynthetic process
G-protein coupled purinergic nucleotide receptor signaling pathway
eating behavior
positive regulation of ion transport
positive regulation of transcription from RNA polymerase II promoter
positive regulation of hormone secretion
establishment of localization in cell
positive regulation of penile erection
positive regulation of ERK1 and ERK2 cascade
response to growth factor
cellular response to ATP
cellular response to purine-containing compound
protein localization to plasma membrane
relaxation of muscle
regulation of blood vessel diameter
regulation of presynaptic cytosolic calcium ion concentration
regulation of synaptic vesicle exocytosis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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