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Alomone Labs, LTD
P2Y4 Receptor Polyclonal Antibody
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FIGURE: 1 / 2
P2Y4 Receptor Antibody (APR-006-200UL) in IHC
Expression of P2RY4 in rat cerebellum - Immunohistochemical staining of rat cerebellum using Anti-P2Y4 Receptor Antibody (#APR-006). A. P2RY4 (red) appears in astrocytic processes (arrows). B.In contrast, P2RY4 does not appearin Purkinje neuronal dendrites stained for calbindin D28k (green) in the same brain section. This demonstrates the restriction of P2RY4 to astrocytic fibers.
Product Details
APR-006-200UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
(C)HEES ISRWA DTHQD, corresponding to residues 337-350 of rat P2RY4, Intracellular, C-terminus
Conjugate
Form
Lyophilized
Concentration
0.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 5% sucrose, 1% BSA
Contains
0.025% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: P2P; P2Y ATP receptor 4; P2Y purinoceptor 4; P2Y4; P2Y4 receptor; P2YR4; purinergic receptor P2Y G-protein coupled 4; purinergic receptor P2Y, G-protein coupled 4; purinergic receptor P2Y, G-protein coupled, 4; pyrimidinergic receptor P2Y, G-protein coupled, 4; RP13-26D14.5; UNR; Uridine nucleotide receptor
Gene Aliases: NRU; P2P; P2RY4; P2Y4; P2Y4R; UNR
UniProt ID: (Human) P51582, (Rat) O35811, (Mouse) Q9JJS7
Entrez Gene ID: (Human) 5030, (Rat) 63843, (Mouse) 57385
phospholipase C-activating G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
transepithelial chloride transport
G-protein coupled purinergic nucleotide receptor signaling pathway
cellular response to prostaglandin E stimulus
G-protein coupled receptor signaling pathway
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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