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Invitrogen
Crotonyl-HIST1H2BC (Lys23) Polyclonal Antibody
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FIGURE: 1 / 1
Crotonyl-HIST1H2BC (Lys23) Antibody (PA5-121399) in ICC/IF
Immunocytochemistry/Immunofluorescence analysis of HIST1H2BC using Crotonyl-HIST1H2BC (Lys23) Polyclonal Antibody (Product # PA5-121399) at a dilution of 1:50 in Hela cells (treated with 30mM sodium crotonylate for 4h) performed on a Leica BondTM system. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked with 10% normal goat serum 30 min at RT. Then primary antibody (... View More
Product Details
PA5-121399
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from Human Histone H2B type 1-C/E/F/G/I protein (17-28aa)
Conjugate
Form
Liquid
Concentration
0.16 mg/mL
Amount
16 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.03% ProClin 300
Storage conditions
-20°C or -80°C if preferred
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody tested in Indirect ELISA
Target Information
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. The protein has antibacterial and antifungal antimicrobial activity. The main transcript variant of this gene is intronless and encodes a replication-dependent histone that is a member of the histone H2B family. This transcript variant lacks a polyA tail but instead contains a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H2B Clustered Histone 4; H2B histone family, member B; H2B-clustered histone 5; H2B/a; H2B/b; H2B/g; H2B/h; H2B/k; H2B/l; H2BC4; HIRA-interacting protein 2; histone 1, H2bd; histone cluster 1 H2B family member d; histone cluster 1, H2bd; Histone H2B type 1-C/E/F/G/I; Histone H2B type 1-D; Histone H2B.1 A; Histone H2B.1 B; Histone H2B.a; Histone H2B.b; Histone H2B.g; Histone H2B.h; Histone H2B.k; Histone H2B.l; unnamed protein product
Gene Aliases: dJ221C16.6; H2B.1B; H2B/a; H2B/b; H2B/g; H2B/h; H2B/k; H2B/l; H2BC10; H2BC4; H2BC5; H2BC6; H2BC7; H2BC8; H2BFA; H2BFB; H2BFG; H2BFH; H2BFK; H2BFL; HIRIP2; HIST1H2BC; HIST1H2BD; HIST1H2BE; HIST1H2BF; HIST1H2BG; HIST1H2BI
UniProt ID: (Human) P62807
Entrez Gene ID: (Human) 3017
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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