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Invitrogen
FGF9 Polyclonal Antibody
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Product Details
PA5-79261
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human FGF9 (150-164aa SNLYKHVDTGRRYYV).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Brain Tissue, HELA whole cell. IHC: Rat Brain Tissue.
Target Information
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development. Expression of the mouse homolog of this gene was found to be dependent on Sonic hedgehog (Shh) signaling. Mice lacking the homolog gene displayed a male-to-female sex reversal phenotype, which suggested a role in testicular embryogenesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: elbow knee synostosis; FGF; FGF-9; Fibroblast growth factor; Fibroblast growth factor 9; fibroblast growth factor 9 (glia-activating factor); GAF; glia activating factor; Glia-activating factor; HBGF-9; Heparin-binding growth factor 9; M-FGF-9; unnamed protein product
Gene Aliases: Eks; FGF-9; FGF9; GAF; HBFG-9; HBGF-9; SYNS3
UniProt ID: (Human) P31371, (Rat) P36364, (Mouse) P54130
Entrez Gene ID: (Human) 2254, (Rat) 25444, (Mouse) 14180
negative regulation of transcription from RNA polymerase II promoter
angiogenesis
osteoblast differentiation
eye development
positive regulation of mesenchymal cell proliferation
chondrocyte differentiation
protein import into nucleus
signal transduction
smoothened signaling pathway
cell-cell signaling
cell proliferation
positive regulation of cell proliferation
fibroblast growth factor receptor signaling pathway
male gonad development
mesenchymal cell proliferation
positive regulation of gene expression
Wnt signaling pathway
substantia nigra development
neurogenesis
cell differentiation
negative regulation of Wnt signaling pathway
male sex determination
lung development
embryonic limb morphogenesis
regulation of cell migration
positive regulation of vascular endothelial growth factor receptor signaling pathway
activin receptor signaling pathway
positive regulation of activin receptor signaling pathway
inner ear morphogenesis
positive regulation of MAPK cascade
positive regulation of smoothened signaling pathway
vascular endothelial growth factor receptor signaling pathway
regulation of timing of cell differentiation
embryonic digestive tract development
embryonic skeletal system development
epithelial cell proliferation
positive regulation of epithelial cell proliferation
positive regulation of cell division
Sertoli cell proliferation
cardiac muscle cell proliferation
positive regulation of cardiac muscle cell proliferation
canonical Wnt signaling pathway
lung-associated mesenchyme development
stem cell proliferation
positive regulation of canonical Wnt signaling pathway
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching
positive regulation of stem cell proliferation
cardiac left ventricle morphogenesis
cardiac ventricle development
multicellular organism development
positive regulation of transcription, DNA-templated
vasculogenesis involved in coronary vascular morphogenesis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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