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This gene encodes polytransferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
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Protein Aliases: ADP-ribosyltransferase (NAD+, poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADP-ribosyltransferase diphtheria toxin-like 2; ADPRT-2; ARTD2; DNA ADP-ribosyltransferase PARP2; HGNC:272; mPARP-2; NAD(+) ADP-ribosyltransferase 2; pADPRT-2; parp 2; PARP-2; Poly [ADP-ribose] polymerase 2; Poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; Protein poly-ADP-ribosyltransferase PARP2
Gene Aliases: Adprt2; Adprtl2; ARTD2; Aspartl2; C78626; PARP-2; Parp2
UniProt ID: (Mouse) O88554
Entrez Gene ID: (Mouse) 11546
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