PDE8A plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase, which has a high affinity for cAMP, may be involved in maintaining basal levels of the cyclic nucleotide and/or in the cAMP regulation of germ cell development.
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Protein Aliases: 5'-cyclic phosphodiesterase 8A; cAMP-specific cyclic nucleotide phosphodiesterase 8A; High affinity cAMP-specific and IBMX-insensitive 3'; High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A
Gene Aliases: HsT19550; PDE8A
UniProt ID: (Human) O60658
Entrez Gene ID: (Human) 5151