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Proteintech
PDIA6 Polyclonal Antibody
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Product Details
18233-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
PDIA6 Fusion Protein Ag12940 (1-440 aa encoded by BC001312)
Conjugate
Form
Liquid
Concentration
0.23 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific to PDIA6.
Immunogen sequence: MALLVLGLV SCTFFLAVNG LYSSSDDVIE LTPSNFNREV IQSDSLWLVE FYAPWCGHCQ RLTPEWKKAA TALKDVVKVG AVDADKHHSL GGQYGVQGFP TIKIFGSNKN RPEDYQGGRT GEAIVDAALS ALRQLVKDRL GGRSGGYSSG KQGRSDSSSK KDVIELTDDS FDKNVLDSED VWMVEFYAPW CGHCKNLEPE WAAAASEVKE QTKGKVKLAA VDATVNQVLA SRYGIRGFPT IKIFQKGESP VDYDGGRTRS DIVSRALDLF SDNAPPPELL EIINEDIAKR TCEEHQLCVV AVLPHILDTG AAGRNSYLEV LLKLADKYKK KMWGWLWTEA GAQSELETAL GIGGFGYPAM AAINARKMKF ALLKGSFSEQ GINEFLRELS FGRGSTAPVG GGAFPTIVER EPWDGRDGEL PVEDDIDLSD VELDDLGKDE L (1-440 aa encoded by BC001312)
Target Information
P5 is a novel protein that was originally identified in humans. Functionally, P5 has been shown to have peptide binding ability and chaperone activity specific to certain proteins. P5 shares several structural similarities to PDI, an important protein of the ER. The deduced amino acid sequence of P5 shows that it contains the ER retention signal KDEL. P5 also contains two CXXC-like motifs, a motif responsible for oxidoreductase activity. These two CXXC motifs are found on the N- and C-terminus of the protein, one at each end. Studies suggest that the N-terminal CXXC motif is more important than the second for isomerase activity. Contrary to most of the PDI-like proteins, P5 is not stress-inducible.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CaBP1; Calcium-binding protein 1; Endoplasmic reticulum protein 5; ER protein 5; protein disulfide isomerase A6; protein disulfide isomerase associated 6; protein disulfide isomerase family A, member 6; Protein disulfide isomerase P5; protein disulfide isomerase-associated 6; protein disulfide isomerase-related protein; Protein disulfide-isomerase A6; thioredoxin domain containing 7; thioredoxin domain containing 7 (protein disulfide isomerase); Thioredoxin domain-containing protein 7
Gene Aliases: 1700015E05Rik; AL023058; C77895; CaBP1; CaBP5; ERP5; P5; PDIA6; TXNDC7
UniProt ID: (Human) Q15084, (Mouse) Q922R8, (Rat) Q63081
Entrez Gene ID: (Human) 10130, (Mouse) 71853, (Rat) 286906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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