Immunogen sequence: AAVNHHSSSD ISPVSNESTS SSPGKEGHSP EGSTVTYHLL GPQEEGEGVV DVKGQVRMEV QGEEEKREDK EDEE
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
PEX14 belongs to the peroxin 14 family. It is a component of the peroxisomal translocation machinery with PEX13 and PEX17 and interacts with both the PTS1 and PTS2 receptors. PEX14 binds directly to PEX17. Defects in PEX14 are the cause of peroxisome biogenesis disorder complementation group K (PBD-CGK) and Zellweger syndrome (ZWS).
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Protein Aliases: NF-E2 associated polypeptide 2; Peroxin 14; Peroxin-14; Peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; Peroxisomal membrane protein PEX14; PEXE; PTS1 receptor docking protein; PTS1 receptor-docking protein
Gene Aliases: dJ734G22.2; NAPP2; PBD13A; PEX14; Pex14p
UniProt ID: (Human) O75381
Entrez Gene ID: (Human) 5195
Molecular Function: receptor