PA1-20196 detects PHD3 in human and mouse samples.
PA1-20196 has been successfully used in Western blot procedures.
The PA1-20196 immunogen is a synthetic peptide corresponding to the C-terminal resiues of human PHD3.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
HIF prolyl hydroxylase 3 is a prolyl hydroxylase that modifies HIF alpha. Classic prolyl hydroxylases are found in the endoplasmic reticulum and modify collagen, whereas HIF is an intracellular protein and the HPH sites do not resemble those modifying collagen. HIF is a transcriptional complex that plays a critical role in oxygen homeostasis. HPH is an essential component of the pathway through which cells sense oxygen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Egl nine homolog 3; egl nine-like protein 3 isoform; egl-9 family hypoxia-inducible factor 3; FLJ21620; HIF prolyl hydroxylase 3; HIF-PH3; HIF-prolyl hydroxylase 3; HIFPH3; HPH-1; HPH-3; Hypoxia-inducible factor prolyl hydroxylase 3; MGC125998; MGC125999; PHD3; Prolyl hydroxylase domain-containing protein 3; SM-20
Gene Aliases: 2610021G09Rik; AI505553; AI648162; EGLN3; Hif-p4h-3; HIFP4H3; HIFPH3; PHD3; SM-20